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By John M. Watson and J. B. Stenlake (Auth.)

ISBN-10: 1483256723

ISBN-13: 9781483256726

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P. falciparum which causes malignant (pernicious) tertian malaria (characterised by febrile paroxysms at irregular intervals approximating to 48 hours in some cases). The life-cycle of all four species is essentially similar. It involves certain mosquito species belonging to the genus Anopheles as intermediate hosts, and passes through four stages : (a) (b) (c) (d) the pre-erythrocytic cycle the exo-erythrocytic cycle the erythrocytic cycle the sexual cycle. (1) The pre-erythrocytic cycle. When a human being is bitten by an infected mosquito, the slender, motile sporozoites of the parasite are injected into the blood stream, which they leave within an hour to invade the liver.

The cercariae leave the snail during rainy weather in masses of mucus known as slime-balls, and must then be ingested by a second intermediate host, the common brown ant, Formica fusca. The definitive host becomes infected by accidentally swallowing infected brown ants. Pathogenesis, both in man and domestic animals, is less severe than in other forms of liver-fluke infection. A number of trematode species infect the liver of domestic animals, as set forth in Table 4. Pulmonary Trematodes There is only one important trematode parasite of the human lung.

Gastrodiscoides hominis. This is a medium-sized (5 by 10 mm) fluke which occurs in India and parts of South-East Asia and attaches itself to the wall of the caecum and ascending colon, producing mucous diarrhoea. The life-cycle is unknown, but a related form occurring in horses (Gastrodiscus aegyptiacus) utilises species of the snail genus Cleopatra as intermediate hosts, the cercariae encysting on vegetation. Man probably acquires the infection by ingesting encysted metacercariae on uncooked vegetables or salads or in water.

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An Introduction to Parasitology by John M. Watson and J. B. Stenlake (Auth.)


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